Sherin S Abdel-Meguid: search on Z-Library

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1

Structural basis of inhibitor selectivity in MAP kinases

Zhulun Wang, Bertram J Canagarajah, Jeffrey C Boehm, Skouki Kassisà, Melanie H Cobb, Peter R Young, Sherin Abdel-Meguid, Jerry L Adams, Elizabeth J Goldsmith

Journal:

Year:

1998

Language:

english

File:

PDF, 1.79 MB

english, 1998

2

Inhibitors of Aspartyl Proteinases

Sherin S. Abdel-Meguid

Journal:

Medicinal Research Reviews

Year:

1993

Language:

english

File:

PDF, 2.51 MB

english, 1993

3

Protein engineering: Editorial overview

John W Erickson, Sherin S Abdel-Meguid

Journal:

Current Opinion in Biotechnology

Year:

1994

Language:

english

File:

PDF, 427 KB

english, 1994

4

Structure of southern bean mosaic virus at 2.8 Å resolution

Abad-Zapatero, Celerino, Abdel-Meguid, Sherin S., Johnson, John E., Leslie, Andrew G. W., Rayment, Ivan, Rossmann, Michael G., Suck, Dietrich, Tsukihara, Tomitake

Journal:

Year:

1980

File:

PDF, 706 KB

1980

5

Unique fold and active site in cytomegalovirus protease

Qiu, Xiayang, Culp, Jeffrey S., DiLella, Anthony G., Hellmig, Brian, Hoog, Susan S., Janson, Cheryl A., Smith, Ward W., Abdel-Meguid, Sherin S.

Journal:

Year:

1996

File:

PDF, 1.54 MB

1996

6

A paradigm for drug discovery using a conformation from the crystal structure of a presentation scaffold

Helms, Larry R., DesJarlais, Renee L., Abdel-Meguid, Sherin S., Wetzel, Ronald, Zhao, Baoguang

Journal:

Natural Structural Biology

Year:

1995

File:

PDF, 773 KB

1995

7

Molecular basis for triclosan activity involves a flipping loop in the active site

Xiayang Qiu, Sherin S. Abdel-Meguid, Cheryl A. Janson, Robert I. Court, Martin G. Smyth, David J. Payne

Journal:

Protein Science

Year:

1999

Language:

english

File:

PDF, 1.25 MB

english, 1999

8

Towards understanding ligand specificity of retroviral proteases. Implications for the design of human immunodeficiency virus type 1 and 2 protease inhibitors

Susan S Hoog, Sherin S Abdel-Meguid

Journal:

Journal of Molecular Structure: THEOCHEM

Year:

1998

Language:

english

File:

PDF, 320 KB

english, 1998

9

Crystallization of alfalfa mosaic virus coat protein as a T = 1 aggregate

Keiichi Fukuyama, Sherin S. Abdel-Meguid, Michael G. Rossmann

Journal:

Journal of Molecular Biology

Year:

1981

Language:

english

File:

PDF, 3.44 MB

english, 1981

10

Crystallization of resolvase, a repressor that also catalyzes site-specific DNA recombination

Patricia C. Weber, David L. Ollis, William R. Bebrin, Sherin S. Abdel-Meguid, T.A. Steitz

Journal:

Journal of Molecular Biology

Year:

1982

Language:

english

File:

PDF, 113 KB

english, 1982

11

Crystallization of 5-enolpyruvylshikimate 3-phosphate synthase from Escherichia coli

Sherin S. Abdel-Meguid, Ward W. Smith, Gary S. Bild

Journal:

Journal of Molecular Biology

Year:

1985

Language:

english

File:

PDF, 122 KB

english, 1985

12

Crystallization of a chymotrypsin inhibitor from Erythrina caffra seeds

Huey-Sheng Shieh, Nancy K. Leimgruber, Mark O. Palmier, Tze-chein Wun, Richard M. Leimgruber, Sherin S. Abdel-Meguid

Journal:

Journal of Molecular Biology

Year:

1990

Language:

english

File:

PDF, 188 KB

english, 1990

13

The location of calcium ions in southern bean mosaic virus

Sherin S. Abdel-Meguid, Takashi Yamane, Keiichi Fukuyama, Michael G. Rossmann

Journal:

Year:

1981

Language:

english

File:

PDF, 402 KB

english, 1981

14

Amino acid sequence of southern bean mosaic virus coat protein and its relation to the three-dimensional structure of the virus

Mark A. Hermodson, Celerino Abad-Zapatero, Sherin S. Abdel-Meguid, Shlomo Pundak, Michael G. Rossmann, Jack H. Tremaine

Journal:

Year:

1982

Language:

english

File:

PDF, 1.23 MB

english, 1982

15

Carbon-13 NMR study of southern bean mosaic virus

Douglas C McCain, R Virudachalam, John L Markley, Sherin S Abdel-Meguid, Michael G Rossmann

Journal:

Year:

1982

Language:

english

File:

PDF, 285 KB

english, 1982

16

Crystals of Escherichia coli single-strand DNA-binding protein show that the tetramer has D2 symmetry

David Ollis, Peter Brick, Sherin S. Abdel-Meguid, Krishna Murthy, John W. Chase, Thomas A. Steitz

Journal:

Journal of Molecular Biology

Year:

1983

Language:

english

File:

PDF, 1.09 MB

english, 1983

17

Structure of a T=1 aggregate of alfalfa mosaic virus coat protein seen at 4·5 Å resolution

Keiichi Fukuyama, Sherin S. Abdel-Meguid, John E. Johnson, Michael G. Rossmann, R. Huber

Journal:

Journal of Molecular Biology

Year:

1983

Language:

english

File:

PDF, 2.20 MB

english, 1983

18

Crystallization of a ribonuclease-resistant fragment of Escherichia coli 5 S ribosomal RNA and its complex with protein L25

Sherin S. Abdel-Meguid, Peter B. Moore, Thomas A. Steitz, R. Huber

Journal:

Journal of Molecular Biology

Year:

1983

Language:

english

File:

PDF, 6.44 MB

english, 1983

19

Crystallization of methionyl porcine somatotropin, a genetically engineered variant of porcine growth hormone

Abdel-Meguid, Sherin S., Smith, Ward W., Violand, Bernard N., Bentle, Larry A.

Journal:

Journal of Molecular Biology

Year:

1986

Language:

english

File:

PDF, 159 KB

english, 1986

20

Preliminary crystallographic study of glycosylated recombinant human renin

Lim, Louis W., Stegeman, Roderick A., Leimgruber, Nancy K., Gierse, James K., Abdel-Meguid, Sherin S.

Journal:

Journal of Molecular Biology

Year:

1989

Language:

english

File:

PDF, 231 KB

english, 1989

21

[Part 1: Biological Sciences] || Cleavage of the Site-Specific Recombination Protein γ δ Resolvase: The Smaller of Two Fragments Binds DNA Specifically

Sherin S. Abdel-Meguid, Nigel D. F. Grindley, Nancy Smyth Templeton and Thomas A. Steitz

Journal:

Proceedings of the National Academy of Sciences

Year:

1984

Language:

english

File:

PDF, 1.13 MB

english, 1984

22

Three-Dimensional Structure of a Genetically Engineered Variant of Porcine Growth Hormone

Sherin S. Abdel-Meguid, Huey-Sheng Shieh, Ward W. Smith, Henry E. Dayringer, Bernard N. Violand and Larry A. Bentle

Journal:

Proceedings of the National Academy of Sciences

Year:

1987

Language:

english

File:

PDF, 924 KB

english, 1987

23

Crystal Structure of Varicella-Zoster Virus Protease

Xiayang Qiu, Cheryl A. Janson, Jeffrey S. Culp, Susan B. Richardson, Christine Debouck, Ward W. Smith and Sherin S. Abdel-Meguid

Journal:

Proceedings of the National Academy of Sciences

Year:

1997

Language:

english

File:

PDF, 1.99 MB

english, 1997

24

Design of Potent and Selective Human Cathepsin K Inhibitors that Span the Active Site

Scott K. Thompson, Stacie M. Halbert, Mary J. Bossard, Thaddeus A. Tomaszek, Mark A. Levy, Baoguang Zhao, Ward W. Smith, Sherin S. Abdel-Meguid, Cheryl A. Janson, Karla J. D'Alessio, Michael S. McQuen

Journal:

Proceedings of the National Academy of Sciences

Year:

1997

Language:

english

File:

PDF, 1.73 MB

english, 1997

25

Inhibition of human immunodeficiency virus-1 protease by a C2-symmetric phosphinate. Synthesis and crystallographic analysis

Abdel-Meguid, Sherin S., Zhao, Baoguang, Murthy, Krishna H. M., Winborne, Evon, Choi, Joong Kwon, DesJarlais, Renee L., Minnich, Michael D., Culp, Jeffrey S., Debouck, Christine

Journal:

Year:

1993

Language:

english

File:

PDF, 1.14 MB

english, 1993

26

Phosphorus-31 nuclear magnetic resonance study of internal motion in ribonucleic acid of southern bean mosaic virus

McCain, Douglas C., Virudachalam, R., Santini, Robert E., Abdel-Meguid, Sherin S., Markley, John L.

Journal:

Year:

1982

Language:

english

File:

PDF, 952 KB

english, 1982

27

High-Resolution X-ray Crystallography Reveals Precise Binding Interactions between Human Nonpancreatic Secreted Phospholipase A 2 and a Highly Potent Inhibitor (FPL67047XX)

Cha, Sun-Shin, Lee, Dennis, Adams, Jerry, Kurdyla, Jeffrey T., Jones, Christopher S., Marshall, Lisa A., Bolognese, Brian, Abdel-Meguid, Sherin S., Oh, Byung-Ha

Journal:

Journal of Medicinal Chemistry

Year:

1996

Language:

english

File:

PDF, 135 KB

english, 1996

28

Three-dimensional structure of a simian immunodeficiency virus protease/inhibitor complex. Implications for the design of human immunodeficiency virus type 1 and 2 protease inhibitors

Zhao, Baoguang, Winborne, Evon, Minnich, Michael D., Culp, Jeffrey S., Debouck, Christine, Abdel-Meguid, Sherin S.

Journal:

Year:

1993

Language:

english

File:

PDF, 1.19 MB

english, 1993

29

An Orally Bioavailable HIV-1 Protease Inhibitor Containing an Imidazole-Derived Peptide Bond Replacement: Crystallographic and Pharmacokinetic Analysis

Abdel-Meguid, Sherin S., Metcalf, Brian W., Carr, Thomas J., Demarsh, Peter, DesJarlais, Renee L., Fisher, Seth, Green, David W., Ivanoff, Lucinda, Lambert, Dennis M.

Journal:

Year:

1994

Language:

english

File:

PDF, 753 KB

english, 1994

30

Human Immunodeficiency Virus Protease Ligand Specificity Conferred by Residues Outside of the Active Site Cavity †,‡

Hoog, Susan S., Towler, Eric M., Zhao, Baoguang, Doyle, Michael L., Debouck, Christine, Abdel-Meguid, Sherin S.

Journal:

Year:

1996

Language:

english

File:

PDF, 446 KB

english, 1996

31

Use of X-ray Co-crystal Structures and Molecular Modeling To Design Potent and Selective Non-peptide Inhibitors of Cathepsin K

DesJarlais, Renee L., Yamashita, Dennis S., Oh, Hye-Ja, Uzinskas, Irene N., Erhard, Karl F., Allen, Andrew C., Haltiwanger, R. Curtis, Zhao, Baoguang, Smith, Ward W., Abdel-Meguid, Sherin S., D'Alessi

Journal:

Journal of the American Chemical Society

Year:

1998

Language:

english

File:

PDF, 71 KB

english, 1998

32

Structural Role of the 30's Loop in Determining the Ligand Specificity of the Human Immunodeficiency Virus Protease †,‡

Swairjo, Manal A., Towler, Eric M., Debouck, Christine, Abdel-Meguid, Sherin S.

Journal:

Year:

1998

Language:

english

File:

PDF, 204 KB

english, 1998

33

Cooperative Structural Dynamics and a Novel Fidelity Mechanism in Histidyl-tRNA Synthetases ‡

Qiu, Xiayang, Janson, Cheryl A., Blackburn, Michael N., Chhohan, Inderjit K., Hibbs, Martin, Abdel-Meguid, Sherin S.

Journal:

Year:

1999

Language:

english

File:

PDF, 814 KB

english, 1999

34

Synthesis and x-ray crystal structure of 1,3,3,4,5,6-hexamethyl-7-thiabicyclo[2.2.1]hept-5-en-2-one 7-anti-oxide

Murray, Roger K., Polley, Judith S., Abdel-Meguid, Sherin S., Day, Victor W.

Journal:

Journal of Organic Chemistry

Year:

1977

Language:

english

File:

PDF, 459 KB

english, 1977

35

A Check on Rational Drug Design: Crystal Structure of a Complex of Human Immunodeficiency Virus Type 1 Protease with a Novel .gamma.-Turn Mimetic Inhibitor

Hoog, Susan S., Zhao, Baoguang, Winborne, Evon, Fisher, Seth, Green, David W., DesJarlais, Renee L., Newlander, Kenneth A., Callahan, James F., Abdel-Meguid, Sherin S., Moore, Michael L., Huffman, Wil

Journal:

Journal of Medicinal Chemistry

Year:

1995

Language:

english

File:

PDF, 1.80 MB

english, 1995

36

Site-Directed Mutagenesis Probing the Catalytic Role of Arginines 165 and 166 of Human Cytomegalovirus Protease

Liang, Po-Huang, Brun, Kimberly A., Feild, John A., O'Donnell, Kevin, Doyle, Michael L., Green, Susan M., Baker, Audrey E., Blackburn, Michael N., Abdel-Meguid, Sherin S.

Journal:

Year:

1998

Language:

english

File:

PDF, 104 KB

english, 1998

37

Characterization of the In Vitro and In Vivo Activity of Monoclonal Antibodies to Human IL-18

Holmes, Steve, Abrahamson, Julie A., Al-Mahdi, Niam, Abdel-Meguid, Sherin S., Ho, Yen Sen

Journal:

Year:

2000

Language:

english

File:

PDF, 126 KB

english, 2000

38

Cathepsin K as a target for the treatment of osteoporosis

Smith, Ward W, Abdel-Meguid, Sherin S

Journal:

Expert Opinion on Therapeutic Patents

Year:

1999

Language:

english

File:

PDF, 243 KB

english, 1999

39

Crystal Structures of the FXIa Catalytic Domain in Complex with Ecotin Mutants Reveal Substrate-like Interactions

Jin, Lei, Pandey, Pramod, Babine, Robert E., Gorga, Joan C., Seidl, Katherine J., Gelfand, Ellen, Weaver, David T., Abdel-Meguid, Sherin S., Strickler, James E.

Journal:

Journal of Biological Chemistry

Year:

2005

Language:

english

File:

PDF, 1.26 MB

english, 2005

40

Structure and Topological Symmetry of the Glyphosate Target 5- Enolpyruvylshikimate-3-Phosphate Synthase: A Distinctive Protein Fold

William C. Stallings, Sherin S. Abdel-Meguid, Louis W. Lim, Huey-Sheng Shieh, Henry E. Dayringer, Nancy K. Leimgruber, Roderick A. Stegeman, Karen S. Anderson, James A. Sikorski, Stephen R. Padgette a

Journal:

Proceedings of the National Academy of Sciences

Year:

1991

Language:

english

File:

PDF, 1.05 MB

english, 1991

41

[Methods and Principles in Medicinal Chemistry] Protein Crystallography in Drug Discovery || Molecular Recognition of Nuclear Hormone Receptor-Ligand Complexes

Babine, Robert E., Abdel-Meguid, Sherin S.

Year:

2003

Language:

english

File:

PDF, 712 KB

english, 2003

42

[Methods and Principles in Medicinal Chemistry] Protein Crystallography in Drug Discovery || Antibiotics and the Ribosome

Babine, Robert E., Abdel-Meguid, Sherin S.

Year:

2003

Language:

english

File:

PDF, 769 KB

english, 2003

43

[Methods and Principles in Medicinal Chemistry] Protein Crystallography in Drug Discovery || Micro-Crystallization

Babine, Robert E., Abdel-Meguid, Sherin S.

Year:

2003

Language:

english

File:

PDF, 456 KB

english, 2003

44

[Methods and Principles in Medicinal Chemistry] Protein Crystallography in Drug Discovery || Engineering Proteins to Promote Crystallization

Babine, Robert E., Abdel-Meguid, Sherin S.

Year:

2003

Language:

english

File:

PDF, 164 KB

english, 2003

45

[Methods and Principles in Medicinal Chemistry] Protein Crystallography in Drug Discovery || Structure-Based Design of Potent and Selective Cdk4 Inhibitors

Babine, Robert E., Abdel-Meguid, Sherin S.

Year:

2003

Language:

english

File:

PDF, 1.05 MB

english, 2003

46

[Methods and Principles in Medicinal Chemistry] Protein Crystallography in Drug Discovery (Babine: Protein Crystall.) || Structure-Based Design of Cathepsin K Inhibitors

Babine, Robert E., Abdel-Meguid, Sherin S.

Year:

2003

Language:

english

File:

PDF, 357 KB

english, 2003

47

[Methods and Principles in Medicinal Chemistry] Protein Crystallography in Drug Discovery (Babine: Protein Crystall.) || High-Throughput Crystallography

Babine, Robert E., Abdel-Meguid, Sherin S.

Year:

2003

Language:

english

File:

PDF, 385 KB

english, 2003

48

[Methods and Principles in Medicinal Chemistry] Protein Crystallography in Drug Discovery (Babine: Protein Crystall.) || The Proteasome as a Drug Target

Babine, Robert E., Abdel-Meguid, Sherin S.

Year:

2003

Language:

english

File:

PDF, 557 KB

english, 2003

49

[Methods and Principles in Medicinal Chemistry] Protein Crystallography in Drug Discovery (Babine: Protein Crystall.) || Front Matter

Babine, Robert E., Abdel-Meguid, Sherin S.

Year:

2003

Language:

english

File:

PDF, 239 KB

english, 2003

50

[Methods and Principles in Medicinal Chemistry] Protein Crystallography in Drug Discovery (Babine: Protein Crystall.) || Subject Index

Babine, Robert E., Abdel-Meguid, Sherin S.

Year:

2003

Language:

english

File:

PDF, 103 KB

english, 2003

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